Home in Winston County at 645 South Columbus Avenue in Louisville, MS

$290,000|Last Updated: Jan 21, 2026

MLS#339789706

645 South Columbus Avenue, Louisville, Winston County, Mississippi

Status:Active

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 1

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Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 4

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 5

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 6

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 7

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 8

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 9

Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 10

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Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 14

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Home in Winston County at 645 South Columbus Avenue in Louisville, MS in Louisville, Mississippi - photo 20

Property Type

Home

Acreage

0.99 acres

County

Winston

Format

Sale

Features

Home
Electricity
Rural Water

Documents

645 South Columbus Ave (Winston) 4.28.26

Description

Step into timeless character and exceptional versatility with this beautifully maintained historic home, formerly operated as a successful Airbnb. Located just three blocks from Downtown Louisville, Mississippi, this spacious one-story residence offers a rare blend of charm, comfort, and income potential.The home features 5 bedrooms, 3 full bathrooms, and 3,449 square feet of heated and cooled living space. Original hardwood floors run throughout, adding warmth and authenticity to every room. The expansive layout includes a large main living area plus a separate second living space, ideal for entertaining, hosting guests, or accommodating multi-generational living. The updated kitchen is both functional and inviting, offering abundant cabinetry and a separate dining area. Additional interior highlights include a sunroom sitting area, perfect for relaxing year-round and enjoying natural light.